Measurement of Dabigatran Concentration Using Finger Prick Dried Blood Spot Sample Collection
نویسندگان
چکیده
منابع مشابه
Finger Prick Dried Blood Spots for HIV Viral Load Measurement in Field Conditions in Zimbabwe
BACKGROUND In the context of a community-randomized trial of antiretrovirals for HIV prevention and treatment among sex workers in Zimbabwe (the SAPPH-IRe trial), we will measure the proportion of women with HIV viral load (VL) above 1000 copies/mL ("VL>1000") as our primary endpoint. We sought to characterize VL assay performance by comparing results from finger prick dried blood spots (DBS) c...
متن کاملValidation and Clinical Evaluation of a Novel Method To Measure Miltefosine in Leishmaniasis Patients Using Dried Blood Spot Sample Collection.
To facilitate future pharmacokinetic studies of combination treatments against leishmaniasis in remote regions in which the disease is endemic, a simple cheap sampling method is required for miltefosine quantification. The aims of this study were to validate a liquid chromatography-tandem mass spectrometry method to quantify miltefosine in dried blood spot (DBS) samples and to validate its use ...
متن کاملCritical sample pretreatment in monitoring dried blood spot citrulline.
BACKGROUND Plasma Citrulline concentration has been correlated to functional enterocyte mass. Dried blood spot (DBS) analysis using LC-MSMS reduces sample amount needed. We optimized DBS elution to increase precision and accuracy of DBS LC-MSMS analysis. METHOD DBS control samples were eluted in varying pH (2.2-7.0) and for varying times (15-75 min) and Cit, Arg and Orn were analyzed using LC...
متن کاملMeasurement of Creatinine from Dried Blood spot by Enzymatic Method
Background: DBS on filter paper has been shown as a feasible matrix for collection, transport and analysis of biochemical analytes. Creatinine, is used as a marker of renal function and staging chronic kidney disease (CKD), often requiring repeated testing for drug dosing in patients who undergo dialysis or those who have had arenal transplant. Blood collected and dried on filter paper would be...
متن کاملHormone measures in finger-prick blood spot samples: new field methods for reproductive endocrinology.
Comparative endocrine studies have notably advanced understanding of ecological factors that contribute to variation in human reproductive function. Such research has relied on methodological advances that permit hormone determinations in samples that are easily and safely collected, stored, and transported, most recently on measurement of steroids in saliva. This report seeks to further expand...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Frontiers in Pharmacology
سال: 2021
ISSN: 1663-9812
DOI: 10.3389/fphar.2021.679431